Abstract
Since the publication of yakriton, the efficacy of the hormone has been reported by different authors outside of this laboratory. On the base of these clinical reports I have made a plan of experimental work concerning toluylendiamine-jaundice and yakriton, from which the following results have been obtained.
1. Toluylendiamine-jaundice is produced in normal dogs, if 2 or 2.5% solution of the diamine is subcutaneously injected in the amount of 1 c. c. per kilo of body weight.
2. Yakriton will act to mitigate the jaundice in its 1/2 R. A. U. (Rabbit-Ammonia-Unit). When it is used in the amount of 2 R. A. U. per kilo almost no bilirubinemia will occur.
