Abstract
The present work was undertaken to test whether or not yak riton, -the detoxicating hormone of the liver, which does not contain the liver principle effectual in human pernicious anemia, -was effectual for experimental phenylhydrazin anemia in rabbits. Only f-classed animals were used in the present experiment.
The result was that the control group which received a daily subcutaneous injection of 1% phenylhydrazin in the amount of 1.5 c.c. per kilo of body weight succumbed on the third injection, while the yakriton group which received, besides phenylhydrazin, a daily injection of yakriton in the amount of 1/10 R. A. U. per kilo of body weight, was able to outlive the third injection of the poison and the ensuing severe anemia.
It has thus been shown, that yakriton, the detoxcating hormone of the liver, is effectual in phenylhydrazin poisoning or in the severe anemia caused by it.