Abstract
(1) The bilateral ligation of the renal vessels (artery and vein together) or the renal veins alone causes in normal rabbits, first a temporary hyperglycaemia immediately after the ligation, and secondly the hyperglycaemia which makes its appearance on the last days, increases with time, and either increases till the death of the animal or decreases finally toward the time of death.
(2) The hyperglycaemia immediately after the bilateral ligation of the renal vessels (artery and vein together) is on a smaller scale and of shorter duration, in comparison with that after the ligation of the renal veins alone.
The former is nothing other than the fixing-operation hyperglycaemia.
The ligation of the renal veins alone in the rabbit, of which the renal nerve plexus has been previously divided, yields exactly the same result as the ligation of the renal vessels (artery and vein altogether) in normal rabbits.
For the superiority of the hyperglycaemia immediately after the bilateral ligation of the renal veins alone over that of the renal vessels (artery and vein together), the renal nerve (as an afferent path) is responsible.
The hyperglycaemia immediately after the bilateral ligation of the renal vessels as well as of the renal veins was not evoked on the bilaterally splanchnectomized rabbit. They are, therefore, of central mechanism.
(3) Roughly speaking, on the whole the severity and duration of the hyperglycaemia on the last days after the ligation are indifferent to the circumstance whether the renal vessels (artery and vein together) or the renal vein alone be ligated bilaterally on the one hand, and whether the rabbit be normal, be bilaterally splanchnectomized or the renal nerve plexus on both sides divided on the other hand.
This form of hyperglycaemia is, therefore, of a mechanism other than the central one.
The hyperglycaemia of this form reaches not seldom a very high degree.
