The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
The Effect of Anticoagulants on the Observed Values of the Oxygen Capacity of Blood Estimated by the Ferricyanide Method
MATAJURO YAMAKITA
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1922 Volume 3 Issue 5-6 Pages 305-316

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Abstract
1. In an amount larger than 0.15 per cent concentration to the ammonia water the addition of potassium oxalate diminishes the values of the oxygen capacity of human blood observed by the ferricyanide method. In the case of the blood of rabbits this effect is produced by an amount larger than 0.2 per cent concentration.
2. The sodium citrate has a similar effect but less marked than potassium oxalate. It produces a recognizable decrease in the observed value of the oxygen capacity of blood in a concentration greater than 0.75 per cent to the ammonia water.
3. Their influence on the observed value of the oxygen concentration is due to their checking action on the laking of blood.
4. There are individual variations in the magnitude of the decrease in the estimated oxygen amount caused by the addition of potassium oxalate of sodium citrate, partly owing to the individual differences of the resistance of the plasma membrane of red corpuscles.
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