Abstract
In the dogs, the operation field of which was sufficiently pre-viously de-afferented, the spleen was excised per laparotomiam, two or three weeks later was tested without applying any anaesthesia absorption of glucose, which was introduced into the stomach through the fistula prepared at once per laparotomiam. The sugar content of the portal and ear vein bloods was determined systematically, and compared to the figures obtained previously in our laboratory. The sole difference in both sets of experiments, the previous and the pre-sent, was that the previous observers fastened dogs supine on the table while we let dogs lie on their left side.
The increase of the sugar content in both kinds of blood, portal and auricular, was this time, that is, in the splenectomized dogs, some-what smaller and arrived at its peak somewhat later; otherwise ex-pressed, the alimentary hyperglycaemia observable in the portal vein blood and the general vein blood was somewhat smaller and pro-gresses somewhat slowly in the splenectomized dogs, but the dura-tion of the hyperglycaemia was similar in the normal and the splen-ectomized dogs.
In passing it may be noted that we were not able to find a diminution of the sugar tolerance by removal of the spleen in our dogs.
