Abstract
Nicotine was intravenously administered into normal. rabbits, anal rabbits indefinitely surviving removal of the suprarenals, and the coeliac and upper mesenteric ganglia, in doses of 0.5 mgrm. and 1 mgrm. per kilo of body weight with the mean blood pressure recording.
The removal does not alter at all the magnitude of the pressure fall occurring immediately after the nicotine injection and that of the subscquent pressure elevation. Neither is the time when they occur altered.
The low resistance of the animals so. operated, on, though they were indefinitely well surviving, against the drug, has been also proved here.
