Abstract
Influence of change of Nacl-concentration (0.3, 1.0, 1.2 and 1.5 per cent) on tissue respiration of kidney cortex of rabbit was investigated by Warburg's second method. In the case of 1.0, 1.2 and 1.5 per cent NaCl-concentration, Ringer's solutions, isosmotic with them, were prepared by adding cane-sugar in definite amounts to the normal Ringer's solution, and the tissue respiration in these canesugar-Ringer's solution was used as the control for those in differently concentrated NaCl-Ringer's solution.
(1) 0.3 percent NaCl concentration in Ringer's solution effected a marked decrease of the tissue respiration in spite of the fact that the solution was made isotonic with the normal Ringer's solution by the addition of cane-sugar.
(2) By 1.0 percent NaCl concentration the tissue respiration was scarcely affected.
(3) When NaCl concentration was 1.2 per cent the decrease of the tissue respiration was marked, especially the decrease in canesugar-Ringer's solution was greater than that in 1.2 o-NaCl-Ringer's solution.
(4) In hypertonic Ringer's solution with 1.5 percent NaCl or in cane-sugar-Ringer's solution (isosmotic with 1.5 o-NaCl-Ringer) the tissue respiration was depressed almost in the same degree in both cases.