Studies on the Detoxicating Hormone of the Liver (Yakriton)

97th Report. The Difference of Urinary Elimination of Phenolsulphonphthalein (Injected Intravenously) in Rabbits with Different Liver Power; and Influence of Yakriton upon It. Part 2

Abstract

Yakriton exerts, as has been published in Part 1¹⁾ of the present paper, an accelerating effect upon the rate of urinary elimination of phenolsulphonphthalein injected intravenously.
1. Now when yakriton was used 30 minutes prior to dye injection, it was not so effective in the amount of 1/4 R. A. U. or 2 R. A. U. (per kilo of body weight) as in the amount of 1 R. A. U. (per kilo) (Cf. Tables 1, 2, 3 and 5).
2. When yakriton was used 30 minutes prior to dye injection, it was not so effective in the amount of 1 R. A. U. (per kilo of body weight) as in the amount of 1/2 R. A. U. (per kilo) (Cf. Tables 2 and 5, of the preceding paper, ¹⁾ and Tables 2 and 5 of this paper).
3. When yakriton was injected in the amount of 1/2 R. A. U. per kilo of body weight for 4 consecutive days, and dye was injected 30 minutes after the last injection of it, the rate of the dye elimination was not accelerated (Cf. Tables 4 and 5).