The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Effect of Vitamin B Administration on Urine of Mothers with Negative Arakawa's Reaction
141st Report of the Peroxidase Reaction. (88th Human Milk Study.)
Haruka Umemura
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1940 Volume 39 Issue 3 Pages 227-247

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Abstract
Human milk negative to Arakawa's reaction is generally B-avitaminotic milk as has has been shown by a number of papers from our Laboratory. Mothers with negative Arakawa's reaction will show an increase of chlorine excretion and urine output per day after an administration of vitamin B, while little or no increase will' be seen in spite of the administration in mothers with positive Arakawa's reaction.
The reason why the increase of the whole day amount of chlorin was the most remarkable in cases with negative Arakawa's reaction, and the least remarkable in cases with positive reaction is very simply explained, if the results published in my preceding papers are taken into consideration. In Arakawa-negative cases an abnormal retention of chlorin occurs in the body, while in Arakawa-positive mothers very little retention, if any, is seen. A remarkable increase in urine output after an administration of vitamin B will demonstrate the fact that in mothers with negative Arakawa's reaction a (-n abnormal) retention of water occurs.
The result of experiment of other authors above cited is parallel with my own result. It is very probable that, viewed from the effect of vitamin B on urine of mothers with negative Arakaw a's reaction, theArakawa-negative human milk will pass for a B-avitaminotic milk* even to the exclusion of other points of view.
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