Abstract
The kobu decoction has both a cardio-tonic and a vasodilatative action. In its action at first the latter overcomes the former and brings forth a slight fall of the blood pressure, while a little later just the reverse is the case, the blood pressure being raised. The urine excretion is augmented owing to its action dilatating the renal blood vessel, which is aided by the diuretic action of mannit contained in it. A large dose of the decoction is followed by a disturbance of the heart beat, together with the dilatation of blood vessels, which may induce the fall of blood pressure and consequent death.
