The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Studies on Melanin
VI. The Genesis of the Nevus Cell
Minor Ito
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1950 Volume 52 Issue 1-2 Pages 95-101

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Abstract
1. By means of the Bielschowsky-Seto's method of neurofibril stain-ing, the author have concluded that the nevus cell is not the production of the “Abtropfung” of epidermis (Unna), but originates from the neuro-ectodermal cell which is homogenetic with the Schwann's cell of Masson.
2. I have recognized the argentaffinity of the Schwann's cell by Bielschowsky-Maresch's staining, and have supported the neurogenic nature of nevus cell. But I am obliged to regect the so-called Abtropfung theory on account of the indifferent attitude of argentaffin fibril against the epi-dermis.
3. The author believes the melanin production depends entirely upon the chemical reaction in the cell which is in contact with the termination of peripheral vegetable nerve, and that it does not matter whether the cell is ectodermal or mesodermal.
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