Studies on the Promoting Agent Obtained from Hout-tuyna cordata (Dokudami) for the Production of the Antibiotic Substance by a Strain of Gram Positive, Spore Bearing Bacilli

Abstract

1) A certain sort of sterol was isolated from Houttuyna cordata (Dokudami), a japanese plant drug, which had the ability to promote the production of the antibiotic substance produced by a certain strain of Gram positive, spore forming bacilli.
2) It was proved, that the sterol isolated from the plant closely resembled sitosterol from the chemical and physical points of view.
3) There was a optimal concentration of this sterol to promote the production of the antibiotic.
4) It was shown that Phenantrene, cholesterol and other similar com-pounds had almost similar activities.