On the Inactivation of Epinephrine Discharged from the Suprarenal Glands
1950 年 53 巻 1-2 号 p. 137-144
詳細
1950 年 53 巻 1-2 号 p. 137-144
The suprarenal vein blood, shut up in the cava vein pouch, prepared in situ in the dog under ether, was tested of the epinephrine by means of the rabbit intestine segment. The course of disappearance of the rabbit intestine segment. The course of disappearance of, epine-phrine in the blood, flowed out from the suprarenal glands and left in the natural conditions as possible, was followed. The epinephrine, as ex-pressed by the intestine movement inhibiting ability, was found di-minished by one-fourth at the end of 10min., by a half at that of 20min., by two-thirds at that of 30min. and so forth. The figures in the earlier periods coincide well with those of Sato, who made similar experiments with the jugular vein and adrenaline solution for a short length of time. When he shut the carotid artery, the inactivation prog-ressed more rapidly.
The rapidity of inactivation of epinephrine in the blood in the natural condition, as possible, is thus proved as definitely more prompt in comparison with the blood, defibrinated; of the latter the present writer has his own experience, the results of which check well with the previous works.
