The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Electrographic Changes Immediately Recorded from the Exposed Human Brain during Cardiazol Convulsion
Toyoji Wada
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1950 Volume 53 Issue 1-2 Pages 59-68

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Abstract
1) In 6 cases of the subjects, electrographic changes induced by car-diazol convulsion were observed by direct recording technique. 2) The direct influence of cardiazol upon the cortex in man was experimented by local application. 3) Excepting of several findings, the general resem-blances in corticogram and EEG recorded via the scalp were capable to recognize. 4) After ending of cardiazol injection, the cortex falls down at first into excitation state, and then, it shifts into convulsion with significant convulsive discharge consisted from spikes of ca. 10 per second, which enlarge gradually those potentials, figuring a sort of damped-vibration possible to express as A=pekx, which may refer an existence of the neuronal process of synchronized propagation of the cortical hyperactivity. 5) In cases of nonconvulsive response, only the cortical excitation was observed. 6) The controlling mechanism of the subcortical part for occurrence of convulsion was commented. 7) Simultaneously with recovering from un-consciousness, there occurs the alpha-rhythm in corticogram, but the com-plete recovery of the subcortical pattern from the abnormal functional state seems to bring the complete recovery of conscious condition.
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