The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Studies on the Antibiotic Substances from Actinomyces
(4th Report) Isolation of Streptomycin from Str. olivaceus
Shina KobayashiJiro SatoNakao IshidaYoriko Owaki
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1952 Volume 55 Issue 2-3 Pages 273-282

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Abstract
Six strains of antagonistic streptomyces of our laboratory collection were determined as streptomycin producing one by their antibacterial spectrum, and concerning with one of these strains (No. 346) designated as Str. olivaceus some taxonomic, studies were made.
By the isolation and purification of the active principle from this culture filtrate, pure HCl-salt was obtained, showing a potency of 800 u per mg. It gave positive Sakaguchi and maltol test and a crystalline reineckate (d. p. 161-164°C).
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© Tohoku University Medical Press
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