A Basic Antibiotic “Roseomycin” Produced by a Strain of Streptomyces roseochromogenus, No. 36

(Studies on the Antibiotic Substances from Actinomyces, 9th Report)

Abstract

A streptothricin-like substance “roseomycin” was purified from culture filtrate of a strain of Str. roseochromogenus. Crystalline reineckate and helianthate was induced. Pure hydrochloride, positive in glucosamin test, was active against gram negative organisms in a similar degree as streptomycin. The toxicity seems to be very low. A high activity against V. comma and against streptomycin resistant organisms seems to be so favourable with this antibiotic.