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Volume 58 (1953)
- Issue 3-4 Pages 199-
- Issue 2 Pages 105-
- Issue 1 Pages 1-
Volume 58, Issue 2
Displaying 1-15 of 15 articles from this issue
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Tatuzi Suzuki, Tsutomu Arai1953 Volume 58 Issue 2 Pages 105-111
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn cats, anesthetized with evipan-sodium, the hypothalamus was stimulated electrically, inserting the electrode with the aid of Horsley-Clarke stereotaxic instrument.
The adrenal vein blood specimens were collected without opening the abdominal cavity and the adrenaline content in the blood specimens was estimated. The blood pressure was recorded simultaneously.
By the stimulation of the ventro-medial as well as the ventro-lateral hypothalamic portion, the blood pressure elevated abruptly. The adrenaline secretion rate before stimulation was 0.03-0.1μg. per kg. per min. and during stimulation it increased remarkably to reach 0.5-5μg. per kg. per min. Soon after stimulation the adrenaline secretion rate resumed in most of cases its initial value.
The authors wish to express their thanks to Prof. M. Wada for his helpful advices during this work.View full abstractDownload PDF (907K) -
Dr. Sh. Yanagawa as the First to Notice Effect of Yakriton to Intensity Peroxidase; Preliminary ReportAkira Sato1953 Volume 58 Issue 2 Pages 112
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
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Tatuzi Suzuki, Ikuro Tanaka, Toshiyuki Ozaki1953 Volume 58 Issue 2 Pages 113-118
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSSampling the adrenal vein blood in dogs without anesthetizing, fastening or evoking pain, the adrenaline secretion rate before and after alloxan was estimated. Blood sugar content was measured simultaneously.
After alloxan the blood sugar content increased definitely. This initial hyperglycemia was followed by the hypoglycemia. The adrenaline secretion rate remained unaltered until an intense hypoglycemia took place. Therefore we can not accept the view of some authors that the initial alloxan hyperglycemia is due to the augmented adrenaline secretion from the adrenals.
At the hypoglycemic phase a definite acceleration of the adrenaline secretion was observed. Its maximum values were measured as 0.14-0.17μg. per kg. per min. from the adrenal gland of one side.
The expense of this investigation has been defrayed in part by a grant from the Ministry of Education. T. S.View full abstractDownload PDF (276K) -
Tom Mori1953 Volume 58 Issue 2 Pages 119-131
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIntracellular distributions of acid and alkaline phosphatase activities in bone marrow imprints obtained from normal rabbit were studied histo-chemically according to Gomori-Takamatsu methods.
The most outstanding result obtained in this experiment was that the negative reaction of mitotic chromosomes in both acid and alkaline phosphatases, which was accompanied with simultaneous intensification of reaction in the cytoplasm. Although -such reaction patterns in both phosphatases are very similar, significances are different from each other.
Negative or minimal reaction of the chromosomes in alkaline phos-phatase represents loss or decrease of enzymatic activity, and increased reaction in the cytoplasm of the same cell shows increased enzymatic activity. On the other hand, negative figures of mitotic chromosomes in acid reaction do not seem to be the specific phenomena restricted to cell division and should be interpreted as the expression of the natural absence of acid phosphatase activity in chromatin of nuclei.View full abstractDownload PDF (1837K) -
III. On the Cholinesterase of Cerebrospinal Fluid in Various DiseasesShigeo Okinaka, Masaki Yoshikawa, Hiroshi Ibayashi, Kazuo Shizume, Fuj ...1953 Volume 58 Issue 2 Pages 133-138
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. ChE activity in the cerebrospinal fluid of 140 patients of various nervous diseases was measured manometrically, using Warburg's apparatus.
2. The value of ChE was expressed with CO2 cubic mm. peroduced per 1 cc. cerebrospinal fluid per 30 minutes.
3. ChE in the cerebrospinal fluid is much weaker than in the serum or the brain tissue, and its value varies independently of change in the serum ChE value.
4. Increased ChE activity of the cerebrospinal fluid was found in tuberculous meningitis and tumor of brain and spinal cord, while in poliomyelitis, progressive paralysis and epilepsy the value was found to be lowered.
5. No abnormal value of ChE in cerebrospinal fluid was confirmed in the following diseases: flaccid and spastic hemiplegia following cerebral hemorrhage, paralysis agitans, periodic paralysis, chorea minor, spastic spinal paralysis, myasthenia gravis, myotonia congenita, progressive muscular dystrophy, etc.
6. The physiological role of ChE in cerebrospinal fluid was discussed.View full abstractDownload PDF (274K) -
IV. On the Relationship between Cholinesterase of Basal Ganglia and Liver DiseasesShigeo Okinaka, Masaki Yoshikawa, Kazuo Shizume, Hiroshi Ibayashi, Aki ...1953 Volume 58 Issue 2 Pages 139-142
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. In order to study the influence of liver disease on ChE concentration of basal ganglia, 14 cases of liver diseases and 14 cases of control patients were investigated.
2. ChE values of putamen, caudate nucleus, and pallidum were measured and compared between these two groups.
3. No decrease of ChE in basal ganglia was confirmed in the group of patients of liver diseases. ChE of basal ganglia appears to remain unchanged in the ordinary liver diseases.View full abstractDownload PDF (181K) -
Katsuya Itahara, Denjiro Musha, Gen Sato, Masataka Kato1953 Volume 58 Issue 2 Pages 143-151
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
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(Studies on the Antibiotic Substances from Actinomyces, 9th Report)Nakao Ishida1953 Volume 58 Issue 2 Pages 153-161
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA streptothricin-like substance “roseomycin” was purified from culture filtrate of a strain of Str. roseochromogenus. Crystalline reineckate and helianthate was induced. Pure hydrochloride, positive in glucosamin test, was active against gram negative organisms in a similar degree as streptomycin. The toxicity seems to be very low. A high activity against V. comma and against streptomycin resistant organisms seems to be so favourable with this antibiotic.View full abstractDownload PDF (375K) -
Studies on the Antibiotic Substances from Actionomyces, 10th ReportMasami Kikuchi1953 Volume 58 Issue 2 Pages 163-168
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1) A streptothricin-like substance, belonging to streptothricin type I was isolated from the culture filtrate of Str. roseochromogenus No. 24.
2) The in vitro activity was nearly the same with that of streptomycin, but 5 mg. injected intravenously into mice, represented a delayed toxicity.
3) Though the crystalline helianthate and reineckate of this salt differ from those of streptothricin type I (roseomycin) in their decomposition points, these compounds seem to be quite similar to the latter in other respects.View full abstractDownload PDF (265K) -
(Studies on the Antibiotic Substances from Actinomyces, 11th Report)Ippei Nagao1953 Volume 58 Issue 2 Pages 169-173
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe activities of 3 antibiotics, streptomycin, roseomycin and No. 259 substance were tested against S. typhosa both in vitro and in vivo. The effectiveness of streptomycin and roseomycin has been proved especially in vivo.View full abstractDownload PDF (197K) -
(Studies on the Antibiotic Substances from Actinomyces, 12th Report)Ippei Nagao1953 Volume 58 Issue 2 Pages 175-178
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSStreptomycin, colistin and several streptothricin-like substances were tested against H. pertussis both in vitro and in vivo.
Many kinds of streptothricins were ineffective, and the most favourable results were obtained with streptomycin and colistin.View full abstractDownload PDF (169K) -
(Studies on Rotatography. 11th Report)Shinji Takahashi, Tadayoshi Matsuda1953 Volume 58 Issue 2 Pages 179-183
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
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Shoichiro Ohara, Mitsuo Sato, Tadashi Sato1953 Volume 58 Issue 2 Pages 185-190
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (303K) -
(Studies on the Antibiotic Substances from Actinomyces, 13th Report)Ippei Nagao1953 Volume 58 Issue 2 Pages 191-194
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effectiveness of roseomycin in vitro and in experimental cholera infections as well as that of choloramphenicol has been proved. On the contrary streptomycin was proved to be ineffective.View full abstractDownload PDF (116K) -
(Studies on the Antibiotic Substances from Actinomyces, 14th Report)Akira Miyamori1953 Volume 58 Issue 2 Pages 195-198
Published: August 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe activities of several kinds of basic antibiotics were tested against Pasteurella tularensis both in vitro and in vivo.
In experimental tularemia infection in mice, both streptomycin and roseomycin showed a similar excellent preventive effect in spite of different activities in vitro.View full abstractDownload PDF (147K)
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