Abstract
Responses of the intragastric temperature to introducing 250cc. of 15-16°C water, 2% alcohol, 0.05 and 0.1% HCl, 0.9% solution of NaCl, 0.07% of caffeine, 0.016% of banthine, 2 and 4% of NaHCO3, and 1% suspension of stomaresin respectively into the stomachs of healthy men, were studied simultaneously with those in the gastric acidity; and the following facts were confirmed.
1. The intragastric temperature reaches the maximum change immediately following introducing of the water, solution or suspension and then recovers.
2. The drugs have no effect upon the maximum change.
3. The drugs display their actions on the recovery in three different forms: the first is the immediate action, the second the intermediate one, and the third the after-effect, which may at times not appear.
4. Accordingly, the change in the intragastric temperature by introducing of the solution or suspension is, as a rule, expressed by two or three exponential functions.
5. The drugs do not exhibit their chemical or pharmacological characteristics, such as gastric secretogogue, antacid and so on, in the change in the intragastric temperature, contrary to that in the gastric acidity.
