The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 60, Issue 1
Displaying 1-14 of 14 articles from this issue
  • Toshihiko Okiawa, Toshio Kurosawa
    1954 Volume 60 Issue 1 Pages 1-9
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    By the method of electrostimulation, the cone- and rod-processes caused by white light were separately' investigated at various parts of the retina.
    1. As the intensity of light increased, both cone- and rod-processes increased in magnitude, but at a certain intensity the rod-process began to decrease, while the cone-process continued to rise.
    2. The rod-process was completely suppressed above a certain intensity. The intensity for complete suppression was found different depending upon retinal location.
    3. The rods nearer to the fovea were found to be more liable to suppression. In other words, the stronger the activity of cones, the greater the depression of rod-activity.
    4. Since the rod-process could clearly be distinguished from the blue-process by their characteristic time constants, the theory that the rods would act as blue receptors in photopic vision, may safely be discarded.
    5. It was discussed that the inactivity of rods in photopic vision may be due to an inhibitory action of cones upon rods.
    We are greatly indebted to Prof. K. Motokawa for his kind guidance and for many valuable discussions.
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  • XXII. Nevus Fusco-caeruleus Acromio-deltoideus
    Minor Itô
    1954 Volume 60 Issue 1 Pages 10
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • CLXIII. A Spectrophotometric Determination Method of Hexoses in Sugar Mixtures and Polysaccharides
    Hajime Masamune, Kiyosi Ogawa
    1954 Volume 60 Issue 1 Pages 11-21
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Probable Identity of Chédiak's and Higashi's Diseases
    Akira Sato
    1954 Volume 60 Issue 1 Pages 22
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • CLXIV. Spectrophotometric Determination of Pentoses in Sugar Mixtures and Polysaccharides
    Hajime Masamune, Kiyosi Ogawa
    1954 Volume 60 Issue 1 Pages 23-31
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • CLXV. A Spectrophotometric Determination Method of Metylpentoses in Sugar Mixtures and Polysaccharides
    Hajime Masamune, Kiyosi Ogawa
    1954 Volume 60 Issue 1 Pages 33-40
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • CLXVI. On Pentose Determination in Nucleic Acids
    Hajime Masamune, Kiyosi Ogawa
    1954 Volume 60 Issue 1 Pages 41-45
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Conditions for hydrolysis and bromination of pentosenucleic acidswere investigated to apply the thionalide method for pentose determination to this class of compounds.
    Through the Grant Committee for Scientific Researches was given a grant from the Education Department, which enabled us to carry out this investigaion. H. Masamune.
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  • Mituyosi Abe
    1954 Volume 60 Issue 1 Pages 47-58
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    The electrical response of the human brain to auditory stimulation was studied by means of Dawson's method of superimposition. The stimulus applied was a continuous tone of 1000 c. p. s. of short duration or a click of high intensity. Though the sound stimulus had on- as well as off-effect, the present experiment was concerned mainly with the on-effects.
    1. The evoked response was triphasic activity beginning with the electronegativity of the pick-up electrode against the indifferent lead on the earlobe. At the highest intensity applied of the stimulus the first negative deflection was started at about 90 msec. after the onset of the stimulus and the peak of the second positive deflection was reached at about 150 msec. These values were not greatly reduced by increasing the intensity of stimulus.
    2. The amplitude increased almost linearly with the stimulus intensity in db units.
    3. The evoked potential was found widely distributed over the scalp, the amplitude being maximal at the vertex. The unresponsiveness of the forehead region was inferred from the finding that the response from that region was reverse in phase to those from the remaining regions.
    4. The refractoriness of the brain following the sound stimulus was measured by applying two clicks of equal intensity as a conditioning and testing stimulus respectively. It was found that the absolutely refractory period was about 0.5 seconds.
    5. When a subject was anesthetized with a barbiturate, the evoked potential increased in size until the stage of 14-per-sec. activity was reached. At the stage of slow waves the evoked potential was lost sight of.
    6. An experiment of electroencephalographic conditioning was made on a subject who responded to the sound stimulus with an evoked on-response followed by a short train of β-waves. A photic stimulus of low intensity and a strong sound of short duration were used as conditioned and unconditioned stimulus respectively. The time interval between two stimuli was about 5 seconds. After a number of application of the combined stimulus it was found that only β-activity appeared as a conditioned excitation of the brain, but that no potential change in form of the so-called evoked response appeared upon conditioned stimulation.
    My hearty thanks are due to Prof. K. Motokawa who furnished me with guidance and criticism in regard to this work.
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  • Naoyoshi Hatchome, Mitsuo Sato
    1954 Volume 60 Issue 1 Pages 59-66
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Nine cases exhibiting cutaneous eruptions among 230 cases of “Yatobyo” (Tularemia in Japan) at Ohara General Hospital during the last sixteen years from Jan., 1937 to Dec., 1952 were studied.
    Most of them were young farmers (6 male and 3 female) from 20 to 30 years of age, who had many chances of contact with wild rabbits in the hunting season, (from November to next February), but only one case, which occurred in July, was caused by tick-bite on the scrotum.
    The eruption developed chiefly during the first or second week of the illness, but in two cases, it developed at the same time with the onset of the disease. The sites of predilection are the face, the neck, the breast and the upper extremities, i.e. parts in the upper half of the body. Moreover, it is an interesting fact that the exanthem was frequently localized at the same side as the adenopathy.
    The eruption was various in type and not specific; sometimes of erythema multiforme or erythema nodosume type, at others urticarial, erythematous or follicular and resembling acne vulgaris. Usually the eruption accompanied fairly itchy or painful feelings.
    It seemed to be an allergic exanthem, which disappeared with no trace in two or three weeks.
    The skin test by heat-killed bacterial suspension was positive in eight cases, and the serum- and slide agglutination tests were positive in all cases. The antigen used was made from bact. tularense, Ebina strain, which was isolated from “Yatobyo” patients in our laboratory.
    We express our deepest gratitude to Dr. Minor Itô, Professor of Tohoku University, for kindly revising this report, and to Dr. S. Ohara, Director of Ohara General Hospital, for his guidance in preparing it.
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  • VII. On the Position of the Abducens Nucleus in Human Embryos, Viewed Ontogenetically
    Shigeaki Yamamoto, Mariko Komatsu, Mitsuyoshi Oikawa, Toshiaki Konno
    1954 Volume 60 Issue 1 Pages 67-70
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Tenth Report Influence of Ingesting Various Solutions on the Intragastric Temperature
    Mitsuo Ohara
    1954 Volume 60 Issue 1 Pages 71-80
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Responses of the intragastric temperature to introducing 250cc. of 15-16°C water, 2% alcohol, 0.05 and 0.1% HCl, 0.9% solution of NaCl, 0.07% of caffeine, 0.016% of banthine, 2 and 4% of NaHCO3, and 1% suspension of stomaresin respectively into the stomachs of healthy men, were studied simultaneously with those in the gastric acidity; and the following facts were confirmed.
    1. The intragastric temperature reaches the maximum change immediately following introducing of the water, solution or suspension and then recovers.
    2. The drugs have no effect upon the maximum change.
    3. The drugs display their actions on the recovery in three different forms: the first is the immediate action, the second the intermediate one, and the third the after-effect, which may at times not appear.
    4. Accordingly, the change in the intragastric temperature by introducing of the solution or suspension is, as a rule, expressed by two or three exponential functions.
    5. The drugs do not exhibit their chemical or pharmacological characteristics, such as gastric secretogogue, antacid and so on, in the change in the intragastric temperature, contrary to that in the gastric acidity.
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  • Eleventh Report A New Thermometer for the Gastrointestinal Temperature Measurement
    Hisayuki Masuda, Mitsuo Ohara, Shigeaki Katsura
    1954 Volume 60 Issue 1 Pages 81-86
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. Using thermistors, a new thermometer to measure the temperatures in two or more regions of the gastrointestinal tract is described.
    2. Comparison of this thermometer with the platinum one used previously was made.
    3. It is proved that this thermometer is a good one to serve the purpose.
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  • Kinshi Mitsuki
    1954 Volume 60 Issue 1 Pages 87-95
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • II. Circumscribed Symmetrical Tuberous Myxedema
    Yoshiro Hamada
    1954 Volume 60 Issue 1 Pages 97-103
    Published: June 25, 1954
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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