Abstract
1. Pig stomach mucus was divided into four fractions including mucus-mucin of Sinokawa. The fractions contained hexosamine (glucosamine and chondrosamine altogether), galactose, L-fucose and mannose in molecular proportions almost coinciding mutually among them.
2. Three of the fractions including the mucus-mucin, which had been yielded comparatively largely, were subjected to alkaline scission at 20°C of the carbohydrate from the major part of the amino acid grouping. The preparations from the different fractions were similar in composition (They contained glucosamine, galactose and L-fucose as sugar components) and group activity as the corresponding preparation from the total mucus.
3. With other portions of the mucus-mucin were prepared the carbohydrate after alkaline treatment at different temperatures and after tryptic digestion. The substances obtained after alkaline scission at 0-3°C and after tryptic digestion possessed higher molecular weight and Group A activity than those in 2. and moreover contained chondrosamine as an additional sugar component. The substance after alkaline cleavage at 30-35°C was found to resemble those in 2. regarding composition and molecular weight, but was less group potent particularly with respect to inhibition of isoagglutination of A erythrocytes.
4. Some deductions were expressed.
Through the Grant Committee for Scientific Researches was given a grant from the Education Department in aid to us. H. Masamune
