Abstract
Macrocytic anemia was found in 16 out of 19 cases of children with nutritional dystrophy.
PGA excretion in the 24-hour urine after oral dose of 10 mg. of PGA was lower in the majority of the children with nutritional dystrophy than in normal subjects, but in a few cases with macrocytic anemia, a relatively high value of the PGA excreted after the test dose was found. In these cases a disturbed utilization of folic acid due to hepatic changes of these children was suggested.