EEG, ECG, respiration, general status and so forth which accompany with rise of pressure in cranium, especially, in ventricles are reported.
1. When pressure in ventricles rise acutely, it may be without danger even at high degrees. On seven epileptics, some of them do not complain of pain so much, even P. I. C. rises to 1, 000mm. H
2O, which is usually dangerous for patients with brain tumor.
2. In both animal and clinical experiments, pulse rate, respiration and blood pressure change in accordance with Cushing phenomena; bradycardia, bradypnea and rise of blood pressure accompany with P. I. C. However, emphasis is made on the point that Cushing phenomena can not be applied to every case. Those with chronic rise of P. I. C. which are observed after brain operation do not accord with it.
3. EEG shows a fixed tendency with rise on P. I. C.; that is, α wave activities for a time at the beginning of the course of the experiment, but they decrease gradually, and δ wave activities increase, the base line of EEG looses its balance and the amplitude reduces with rise on P. I. C. In cats, EEG almost diminishes at 1, 500mm. H
2O. In clinical experi-ments the above mentioned tendency is noticed when P. I. C. rises to 1, 000mm. H
2O. EEG activities, differes by individuals but generally the changes are little, and few are without change.
4. Some pathological discharge of ECG, i.e., ventricular extrasystole, sinus arrhythmia, alternative pulse, atrioventricular block, etc., accompany with rise of P. I. C. Probably, these tendencies are caused by unbalance of both the function of vagus and sympathetic nerve, as the result of anemia in center of autonomic nervous system, which accompanies with rise of P. I. C.
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