The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Biochemical Studies on Carbohydrates
CCXI. A KIK Factor (V) from Cancerous Urine and the Corresponding Substance from Normal Urine
Hirosi Kaketa
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1958 Volume 67 Issue 4 Pages 319-328

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Abstract
1. Urines of stomach-, liver-, lung- and mamma-cancer patients and normals were fractioned, separating an anemia-inducing product from each of the cancerous urines and a non-anemia-inducing product from normal urine in an electrophoretically homogeneous state.
2. The products were investigated chemically and physically. They are all mucoproteins composed of galactosamine, glucosamine, galactose, mannose, L-fucose, xylose and/or lyxose, sialic acid and many amino acids.
3. Those from the various cancerous urines resemble one another in electrophoretic mobility, optical rotation, ultraviolet absorptivity, composition and anemia-inducing potency, in other words, they are identical with one another. That from normal urine differs from those above in all the respects as well as in yield.
4. The cause of difference among KIK factors according to secretion or excretion is discussed.
Through the Grant Committee for Scientific Researches the Ministry of Education gave a grant in aid to us, which is gratefully acknowledged. H. Masamune.
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© Tohoku University Medical Press
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