The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Effect of Diisopropylfluorophosphate on the Secretary Function of the Adrenal Medulla
Mikio Araki
Author information
JOURNAL FREE ACCESS

1958 Volume 68 Issue 3-4 Pages 271-277

Details
Abstract
The adrenal venous blood was sampled by the lumbar route method from dogs anesthetized with Evipan-sodium and was analysed for adrenaline by the Bloor and Bullen's colorimetric method.
The adrenaline secretion rate was not altered by the intravenous injection of DFP in a dose of 1.0mg. per kg.
On receiving acetylcholine in a dose of 1.0mg. per kg., the adrenaline secretion rate was increased, and this action of acetylcholine was enhanced definitely by the pretreatment of DFP in doses of 0.3-1.0mg. per kg.
An intravenous injection of carbaminoylcholine in a dose of 0.4mg. per kg. induced a considerable increase in the adrenaline secretion rate. However, this action was found to be almost unaffected by the previous administration of DFP in a dose of 1.0mg. per kg.
Content from these authors
© Tohoku University Medical Press
Previous article Next article
feedback
Top