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Mizu Kojima, Mamoru Takagaki, Tsutomu Watanuki, Masayuki Ogata, Masabu ...
1958 Volume 68 Issue 3-4 Pages
207-224
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Yoshikazu Nakamura, Koshiro Hatanaka
1958 Volume 68 Issue 3-4 Pages
225-237
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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1. The effects of denervation of the cat's sweat glands on their responsiveness to adrenaline, nicotine and mecholyl were studied by measuring the minimum effective concentrations of these agents for eliciting the sweat responses when injected subcutaneously into the foot-pads.
2. The sensitivity of the sweat glands to all these test agents was increased by denervation, its maximum being reached at the end of about a week after denervation. The supersensitivity persisted usually for about 2 to 3 weeks, after which the sensitivity diminished more or less progressively. In general, the supersensitivity was a more regular and more certain effect of the denervation than the hyposensitivity at least for the observation period of about one month and a half after denervation.
3. Adrenaline was proved to have the property of eliciting the sweat response in the cat's foot-pads when applied locally or systemically. This response was abolished by dihydroergotamine, but not by atropine and procaine.
4. The sweat responses to intravenous and intra-arterial injections of adrenaline were exaggerated for a certain period following the denervation. This may be explained as being due to the increased sensitivity to adrenaline of the denervated sweat glands themselves.
We wish to express our thanks to Professor Masao Wada for his guidance and advice throughout this work.
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Koiti Motokawa, Mituru Ebe, Mitsuo Komatsu
1958 Volume 68 Issue 3-4 Pages
239-248
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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It was shown in previous papers that spreading induction was reflected and refracted at the boundary between dark-adapted and lightadpated retinal parts. In the present experiments evidence has been provided that spreading induction shows diffraction. A pair of patches, an inducer and a detector, was used together with a patch whose retinal image served as a diffraction grating. The inducer was a patch to initiate spreading induction, and the detector a devide to detect the arrival of the spreading induction from the inducer. The grating patch consisting of light and dark stripes was presented half-way between the inducer and the detector so that the spreading induction from the inducer had to traverse the retinal image of the grating to reach the detector. Under these conditions the arrival of spreading induction was found only at several discrete parts of the detector in a manner similar to light bands of a diffraction spectrum. An arrangement of patches imitating Rowland's concave grating was found most suitable for this experiment. The wavelength of spreading induction was measured by this method, and values about 30 μ and 50 μ were obtained for yellow and blue spreading inductions respectively.
The wave-length was longer in the order:
red<yellow<green<blue. It is reverse to the order of spectral lights concerning wave-lengths.
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Koiti Motokawa, Toshihiko Oikawa, Kyoji Tasaki, Eizo Yamashita
1958 Volume 68 Issue 3-4 Pages
249-256
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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A KCl-filled microelectrode was inserted into the retina of the carp to record an intracellular slow potential. Especially flicker and fusion of this potential in response to intermittent light was studied with special reference to temperature. The light-dark ratio of the stimulus was 1:1.
1. The critical fusion frequency (CFF) was different according to the types of elements. In the N-element which showed a simple negativegoing response to a steady illumination, the CFF was lower than that of the A-element which showed a positive overawing at cessation of illumination. For example, the CFF of a N-element was 48 cps. at 29°C, while that of an A-element was 72 cps. at the same temperature.
2. The CFF-log intensity relation was investigated at three different temperatures. The general trend of the relation was very similar to those obtained by the psychophysical and behavorial methods, and a single smooth curve was sufficient to represent the data at each temperature.
3. The maximal CFF was found higher with increasing temperatures, and this feature and the general trend of the CFF-log intensity curve could be accounted for on the basis of the photochemical theory as formulated by Jahn.
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Kiichiro Suzuki, Yoshio Toratani, Tetsuo Oiso, Hisayuki Yamashita
1958 Volume 68 Issue 3-4 Pages
257-263
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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By means of Motokawa's method of electric flicker (EF) we measured changes of electric flicker value (EFV) of 3 subjects caused by mental work (calculation of statistics) and exercise (running and steptests).
1. Immediately after mental work, the EFV increased. Recovery was very slow and much prolonged ; the difference between the EFVs measured before and 60 minutes after mental work was found statistically significant.
2. Immediately after exercise the EFV increased far more remarkably than after mental work, but recovery was very prompt; the difference of EFV from the control value was no longer significant after 20-30 min.
3. Effects of light gymnastics performed after mental work were investigated. Recovery from fatigue caused by mental work was facilitated by light gymnastics.
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Kazukuni Yamashita, Takaaki Mitamura, Masaaki Inoue, Hirobumi Akimoto
1958 Volume 68 Issue 3-4 Pages
265-270
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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The experiments were performed in dogs anesthetized with Evipansodium. The adrenal venous blood was collected through the lumbar route and was estimated for adrenaline using the arseno-molybdic acid method of Bloor and Bullen. Intravenous injection of acetylcholine in doses of 2.0mg., 1.5mg. or 1.0mg. per kg. of body weight was made after administrations of atropine in doses of 1mg. and 10mg. per kg., respectively. In some cases it was also made without administering atropine previously.
After the administration of atropine in a dose of 10mg. per kg., a definite increase in the adrenaline secretion rate was elicited by the injection of acetylcholine in almost the same magnitude as that caused by acetylcholine after atropine in a dose of 1mg. per kg. or without atropine.
From these experimental results, it may be concluded that the adrenaline-secretory action of acetylcholine is not inhibited even by large doses of atropine.
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Mikio Araki
1958 Volume 68 Issue 3-4 Pages
271-277
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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The adrenal venous blood was sampled by the lumbar route method from dogs anesthetized with Evipan-sodium and was analysed for adrenaline by the Bloor and Bullen's colorimetric method.
The adrenaline secretion rate was not altered by the intravenous injection of DFP in a dose of 1.0mg. per kg.
On receiving acetylcholine in a dose of 1.0mg. per kg., the adrenaline secretion rate was increased, and this action of acetylcholine was enhanced definitely by the pretreatment of DFP in doses of 0.3-1.0mg. per kg.
An intravenous injection of carbaminoylcholine in a dose of 0.4mg. per kg. induced a considerable increase in the adrenaline secretion rate. However, this action was found to be almost unaffected by the previous administration of DFP in a dose of 1.0mg. per kg.
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Masaaki Inoue
1958 Volume 68 Issue 3-4 Pages
279-284
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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The noradrenaline and adrenaline content of the adrenal gland in toads was estimated by the permanganate method of Suzuki and Ozaki.
In normal toads the noradrenaline content was 0.110 (0.078-0.145)mg. per kg. of body weight and that of adrenaline was 0.187 (0.154-0.244)mg., the relative noradrenaline content being 37 (31-46)%.
Ten hours after insulin application the adrenaline content was found to be reduced markedly, while the noradrenaline content remained almost unaltered.
The decrease in the adrenaline content of the adrenal causable by insulin hypoglycemia was nullified by the section of the splanchnic nerves.
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Report I Fluctuations of the Bilirubin Content in Liver Bile after the Operation for Various Biliary Tract Diseases
Tomonobu Satô
1958 Volume 68 Issue 3-4 Pages
285-292
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Report II Clinical Consideration on the Bilirubin Content of Bile in Patients with Various Biliary Tract Diseases
Tomonobu Satô
1958 Volume 68 Issue 3-4 Pages
293-301
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Report III Bilirubin Content of Bile in Dogs with Pathologically Changed Biliary Tract
Tomonobu Satô
1958 Volume 68 Issue 3-4 Pages
303-307
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Report IV Experimental Study on Bilirubin Content of Bile in Dogs fed on High or Low Protein
Tomonobu Satô
1958 Volume 68 Issue 3-4 Pages
309-312
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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CCXIX. Total Synthesis of Lactosamine-octaacetate
Takasi Okuyama
1958 Volume 68 Issue 3-4 Pages
313-317
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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CCXX. On Synthesis of N-Acetylallolactosamine
Takasi Okuyama
1958 Volume 68 Issue 3-4 Pages
319-320
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Fifth Report KIK-inactive Toxohormones from Urines of Cancer Patients with Original Tumor in Different Organs
Hajime Masamune, Hirosi Kaketa, Sin-iti Abe
1958 Volume 68 Issue 3-4 Pages
321-324
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Haruki Wakasa
1958 Volume 68 Issue 3-4 Pages
325-335
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Tsuneo Nakagawa
1958 Volume 68 Issue 3-4 Pages
337-346
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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I. Analysis of Patterns of Activity of the Abdominal Wall Muscles in Normal Adults
Keiichi Ono
1958 Volume 68 Issue 3-4 Pages
347-354
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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An electromyographic study on the abdominal wall muscles in normal adults was performed by the use of surface electrodes after Floyd and Silver with eight-channel electroencephalograph. The subjects employed were 15 healthy adults, 10 males and five females, ranging in age from 17 to 40 years.
Results obtained are as follows:
1. Head raising gives rise to the dominant activity of the rectus in supine posture. When the intra-abdominal pressure is raised in supine posture the action of the oblique muscles, especially of the internal, is clearly observed. The rectus plays a passive role and is only involved when the trunk is flexed at the same time. It is, therefore, evident that there is a close relationship between the intra-abdominal pressure and the internal obliques.
2. When the subjects are at rest in a standing posture, the internal oblique muscles demonstrate a state of slight activity.
The amplitude of this discharge is 50-100 μV. This phenomenon indicates that this continuous activity of the internal obliques is being done as a result of the stretch reflex which the weight of the intra-abdominal viscera provokes on the internal obliques. It seems, therefore, that the internal obliques play an important role as an anti-gravity muscle supporting the intra-abdominal viscera.
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II. Peculiarity of the Abdominal Wall Muscles in Visceroptotic
Keiichi Ono
1958 Volume 68 Issue 3-4 Pages
355-361
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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An electromyographic investigation on the abdominal wall muscles in visceroptotic subjects was performed using an eight channel electroence-phalograph with surface electrodes in 30 cases of visceroptosis. The results obtained are as follows:
1. In visceroptosis, the resting discharge from the internal obliques in erect posture is more than normal; the waves of discharge have an amplitude of 100-200 μV in these cases, while below 100 μV in normal.
2. This is apparently due to the fact that in visceroptosis the internal oblique which support the intra-abdominal viscera, especially stomach and colon, may have to work harder than in normal.
3. It may be, therefore, impossible to discuss the pathologic physiology of visceroptosis without asking about the anti-gravity function of the internal oblique muscles.
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III. Therapeutic Significace of the Abdominal Bandage for Visceroptosis
Keiichi Ono
1958 Volume 68 Issue 3-4 Pages
363-371
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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For the purpose of inquiring into the therapeutic significance of the abdominal bandage for visceroptosis, an electromyographic investigation on the abdominal wall muscles was performed using surface electrodes and an eight channel electroencephalograph. The subjects employed were fifteen cases of visceroptosis and ten healthy adults.
Results obtained are as follows:
1. The therapeutic significance of the abdominal bandage for visceroptosis exists in the reinforcement of the anti-gravity function of the internal obliques rather than lifting up the intra-abdominal viscera.
2. When visceroptosis is to be treated with a bandage, it will be necessary to determine the suitable part of the abdominal wall on which to apply moderate pressure so that the internal obliques will be correctly _??_reinforced.
3. The symptoms of ptosis are intensified by the applying of pressure on the upper abdominal wall. Namely, the “Corset theory” which had been considered as a cause of visceroptosis since early times was given its endorsement by this experiment.
4. Therefore, the use of unsuitable corset and belt, or upward slipping of the bandage from the lower position are opposed to the purpose of treatment for visceroptosis.
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II. Mechanism of Dust-macule Formation
Takao Takizawa, Hiroshi Haseyama, Masabumi Kuroda
1958 Volume 68 Issue 3-4 Pages
373-378
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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Masaaki Inoue
1958 Volume 68 Issue 3-4 Pages
379-383
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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In toads the spinal root pathway of the adrenaline-secretory fibers to the adrenal gland was studied, taking the depletion of the adrenal gland as an indicator of augmented adrenaline secretion. The adrenaline and noradrenaline content of the adrenal gland was estimated by the use of the permaganate method.
The adrenaline-secretory fibers were found to run through the 3rd, the 4th and the 5th ventral spinal roots.
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Second Report Two Disaccharides Isolated from Skin Itinsulfate
Mei Satake
1958 Volume 68 Issue 3-4 Pages
385-397
Published: October 25, 1958
Released on J-STAGE: November 28, 2008
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A fraction containing the least possible quantity of glucuronic acid was separated from skin itinsulfate of pig, and two disaccharides chondrosine and “dermosine” which is galactosamine-3-L-iduronide were isolated from its hydrolysate. The properties of those disaccharides are described.
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