Changes of Blood ATP, Inorganic Phosphorus and Blood Sugar after Injection of Glucuronic Acid in Diabetics and Nondiabetics

Abstract

The effects of glucuronic acid on blood ATP (adenosine triphosphate), inorganic phosphorus and blood sugar were observed in nine diabetic patients and seven nondiabetic adults. The blood ATP (measured as seven minutes' hydrolyzed phosphorus) was elevated distinctly after an initial decrease by the intramuscular injection of 1000mg. of sodium glucuronate. This injection caused a decrease in blood inorganic phosphorus and also a depression of blood sugar in diabetics as well as in nondiabetics. There were no statistically significant differences in the maximum increase rate (in per cent) of blood ATP, and the maximum decrease rate of blood inorganic phosphorus between the diabetic group and the nondiabetic group.