The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Changes of Blood ATP, Inorganic Phosphorus and Blood Sugar after Injection of Glucuronic Acid in Diabetics and Nondiabetics
Yoshio GotoYukio UjiieAkira TakanamiAkihiko KuwanoTatsuru Uchiyama
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1959 Volume 69 Issue 2-3 Pages 137-141


The effects of glucuronic acid on blood ATP (adenosine triphosphate), inorganic phosphorus and blood sugar were observed in nine diabetic patients and seven nondiabetic adults. The blood ATP (measured as seven minutes' hydrolyzed phosphorus) was elevated distinctly after an initial decrease by the intramuscular injection of 1000mg. of sodium glucuronate. This injection caused a decrease in blood inorganic phosphorus and also a depression of blood sugar in diabetics as well as in nondiabetics. There were no statistically significant differences in the maximum increase rate (in per cent) of blood ATP, and the maximum decrease rate of blood inorganic phosphorus between the diabetic group and the nondiabetic group.

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