The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
A Histometrical Study of the Anterior Pituitary Glands of Male Mice from Pre-mature Stage to Puberth
Tom MoriNoriko FujimoriAkinobu HagaShigetaka MurakamiSeichoku SugawaraYoshikatsu Honda
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1960 Volume 71 Issue 4 Pages 347-357

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Abstract

1. The development of the anterior pituitary cells of male mice from pre-mature stage to puberty was studied histometrically. For the cell-counting, sections cut along the selected sagittal planes and stained with PAS-orange G-hematoxylin were used.
2. According to the staining property and the localization, the existence of two types of PAS-positive basophils corresponding to the beta. and the delta cells was confirmed.
3. The number of the basophils and the percentage of the acidophils showed steady rise until the end of the 6th week, while the percentage of the chromophobes fell abrest during the same period. The percentage of the basophils remained almost constant. The growth in size of the anterior lobe was also found in the younger stage before the end of the 6th week.
4. From these findings, it was pointed out that a remarkable retardation in the quantitative development of the anterior pituitary takes place at the end of the 6th week in the male mice of dd-strain.

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© Tohoku University Medical Press
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