The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Molisch-positive Mucopolysaccharides of Gastric Cancers as Compared with the Corresponding Components of Gastric Mucosae
Fifth Report: On MPSs (Mucopolysaccharides) III
Hajime MasamuneHiroya KawasakiHyogo SinoharaShoichi AbeSin-iti Abe
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1960 Volume 72 Issue 4 Pages 328-337

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Abstract
1. MPSs III, cancerous and noncancerous, were prepared by modified procedures of that described in the First Report1) and examined physically, chemically and biologically.
2. Electrophoretic mobility studies showed that the cancerous MPS III was more acidic than the noncancerous.
3. MPSs III were found to contain galactosamine, glucosamine, galactose, fucose and sialic acid as sugars. Total hexosamine contents were almost on the same level in both substances. The cancerous MPS III contained some what less amounts of galactose and fucose, but markedly larger amount of sialic acid than the noncancerous.
4. Either preparations do not possess group activity within ABO classification. They are also devoid of anemia-inducing activity. The cancerous MPS III was tested for toxohormone activity and found weakly active.
This work was aided by a grant for scientific researches from the Ministry of Education.
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© Tohoku University Medical Press
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