1. MPSs III, cancerous and noncancerous, were prepared by modified procedures of that described in the First Report1) and examined physically, chemically and biologically.
2. Electrophoretic mobility studies showed that the cancerous MPS III was more acidic than the noncancerous.
3. MPSs III were found to contain galactosamine, glucosamine, galactose, fucose and sialic acid as sugars. Total hexosamine contents were almost on the same level in both substances. The cancerous MPS III contained some what less amounts of galactose and fucose, but markedly larger amount of sialic acid than the noncancerous.
4. Either preparations do not possess group activity within ABO classification. They are also devoid of anemia-inducing activity. The cancerous MPS III was tested for toxohormone activity and found weakly active.
This work was aided by a grant for scientific researches from the Ministry of Education.
