The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Experiments on the Chemotherapeutic Treatment of Carcinoma with Citral and Citronellal and those Combined with PCMB
Shungo OsatoHajime MoriMichio Morita
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1961 Volume 75 Issue 3 Pages 223-233

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Abstract

1. In the present paper, animal experiments of the chemotherapy with Citronellal in MH 134 (adenocarcinoma) of C3H FI strain are reported.
2. About 30 to 50% of tumor animals were cured when the chemotherapy with Citronellal was started on the same day as inoculation of tumor.
3. When the administration of Citronellal was begun on the third day of tumor inoculation, the result of chemotherapy was lower, yet the effect was quite obvious. In this case the efficacy was very much promoted with the combined use of PCMB.
4. Our expectation in the co-operation of PCMB with Citronellal and Citral, based upon the electron microscopic study of tumor cells mentioned in the previous paper, is verified in this report.

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