Abstract
In dogs anesthetized with sodium pentobarbital, the adrenal venous blood was collected by the lumbar route method. Differential estimation of adrenaline and noradrenaline contents of the whole blood samples was made by a modification of the Weil-Malherbe and Bone method. After atropinization, an intravenous injection of acetylcholine, carbaminoylcholine, or benzoylcholine was made.
By the injection of choline esters the adrenal adrenaline and noradrenaline secretion rates were increased markedly. The relative amount of noradrenaline to the total catecholamines liberated after injection of carbaminoylcholine was on the average 31% and that after acetylcholine and benzoylcholine was 14% and 11%, respectively.
The author is grateful to Dr. K. Hirai who provided valuable assistance in the present study and to Prof. T. Suzuki for criticizing the manuscript.
