Pathophysiology of Plasmin System
II. Fibrinolysis and Plasmin (Activator)-Inhibitor Ratio
1963 Volume 78 Issue 4 Pages 363-369
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1963 Volume 78 Issue 4 Pages 363-369
The following results were obtained by the estimation of fibrinolysis in plasma, proteolytic activity of euglobulin fraction and trypsin inhibitor.
1. Plasma did not always evidence fibrinolysis in the presence of high euglobulin activity. Nor did it evidence failure of fibrinolysis in the presence of low euglobulin activity.
2. Trypsin inhibitor was more closely related to the occurrence of fibrinolysis in plasma than the proteolytic activity of euglobulin fraction.
3. The sera showed fibrinolysis by the diluted plasma clot method when the PIR values were more than 1.0. Contrariwise, no fibrinolysis occurred when PIR values were less than 1.0.
