The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
A Dextrorotatory Polysaccharide of Very High Anticoagulant Activity Newly Isolated From the Whale's Lung and Intestine
Koroku HashimotoMasao MatsunoZensaku YosizawaTetsuo Shibata
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1963 Volume 81 Issue 1 Pages 93-95

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Abstract
A dextrorotatory polysaccaride recently isolated from whale lung and intestine has been demonstrated to have a high anticoagulant activity. in vitro and in vivo. Protamine neutralization and lipolytic activities are similar to those of beef heparin. The sulfur content of the new polysaccharide is lower than that of beef heparin. The new substance was used successfully as an anticoagulant in 221 dog perfusion experiments.
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