Abstract
Statistical and clinical studies were carried out in 1443 patients with tumors of reticuloendothelial system (RES) and 2188 patients with tumors of lymphoid tissue treated between 1953 and 1962 at universities and other hospitals in Japan. It is noteworthy that the incidence of lymphoid reticulum cell sarcoma is high in Japan. However, the incidence of tumors of RES and lymphoid tissue is still lower than that in most of other countries. As to the age distribution there was a significant difference between Japan and other countries, and it has been suggested that the incidence of lymphoid reticulum cell sarcoma in over 55 years of age was actually increasing. There were some differ-ences in frequency of initial symptom, presenting symptoms and signs between tumors of RES except lymphoid reticulum cell sarcoma and lymphoid tissue. The characteristic hematologic findings have not been observed at the initial phase of tumors of RES and lymphoid tissue. Also in this paper pathophysiology, effects of therapies and survival time of patients with tumors of RES and lymphoid tissue have been reported.
