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Volume 82 (1964)
- Issue 4 Pages 293-
- Issue 3 Pages 181-
- Issue 2 Pages 93-
- Issue 1 Pages 1-
Volume 82, Issue 1
Displaying 1-8 of 8 articles from this issue
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Kiyoji Kimura1964 Volume 82 Issue 1 Pages 1-20
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSStatistical and clinical studies were carried out in 1443 patients with tumors of reticuloendothelial system (RES) and 2188 patients with tumors of lymphoid tissue treated between 1953 and 1962 at universities and other hospitals in Japan. It is noteworthy that the incidence of lymphoid reticulum cell sarcoma is high in Japan. However, the incidence of tumors of RES and lymphoid tissue is still lower than that in most of other countries. As to the age distribution there was a significant difference between Japan and other countries, and it has been suggested that the incidence of lymphoid reticulum cell sarcoma in over 55 years of age was actually increasing. There were some differ-ences in frequency of initial symptom, presenting symptoms and signs between tumors of RES except lymphoid reticulum cell sarcoma and lymphoid tissue. The characteristic hematologic findings have not been observed at the initial phase of tumors of RES and lymphoid tissue. Also in this paper pathophysiology, effects of therapies and survival time of patients with tumors of RES and lymphoid tissue have been reported.View full abstractDownload PDF (734K) -
Kaneyoshi Akazaki, Haruki Wakasa1964 Volume 82 Issue 1 Pages 21-41
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe classification of tumors of RES has been reported on the basis of the authors' criteria of the RES1-5). Incidence of tumors of RES in Japan has been compared with that in America and some views on the types of tumors of RES are also discussed. In Japan, it is a remarkable fact that incidence of reticulosarcoma is the highest among all tumors of RES.
As for the types of tumors of RES, there are similar points in reticuloma and histiocytoma, namely, both tumors are rare and have the same nature except that histiocytoma is rich in fibrous stromal tissue owing to the site of its subcutaneous origin.
The authors have classified reticulosarcoma into three forms according to the site of growth as follows, i) lymphatic reticulosarcoma ii) myelogenic reticulo-sarcoma iii) reticulosarcoma originated from other organs and tissues. Most of reticulosarcomas belong to the lymphatic reticulosarcoma; the other two forms are very scarce. The so-called stellate cell sarcoma of the liver should be called hepatic reticuloendothelioma and Ewing's tumor is identical with reticuloendo-thelioma of the bone marrow. These tumors are scarce, especially hepatic reticuloendothelioma.
The reports on Brill-Symmers disease are scarce in Japan, especially those of autopsy cases. Lindau's tumor should be named angioreticuloma according to the character of component cells.View full abstractDownload PDF (2913K) -
Yukio Ishibashi1964 Volume 82 Issue 1 Pages 42-47
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSWe investigated immune responses of tumor-bearing host to understand some possible relationships between reticuloendothelial system and neoplasma.
The lower levels of antibody production to heterologous antigens were observed in tumor-bearing animals, as compared with tumor free controls. In cancer patients, however, we failed to find depressions of humoral immune responses even in the later stages. On the other hand, delayed type of hypersensitivity, as determined by tuberculin reaction and skin homograft reaction, is significantly weaker in both cancer-bearing animals and patients. This suggests that such a qualitative deficiency of immune responses is responsible for the development and progression of neoplasm. It might, therefore, be supposed that host can counteract neoplastic disease by correcting this deficiency. That bone marrow transplantation from closely related donors might help in this approach is suggested.View full abstractDownload PDF (290K) -
Taizo Suzuki, Hachiro Inomata1964 Volume 82 Issue 1 Pages 48-51
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBy selective stimulation of intramural sympathetic nerve fibers, the inhibitory post-synaptic potential in intestinal smooth muscle cell could be recorded intracellularly. This inhibitory potential, with the exception of direction, was found to be similar, in many of its properties, to the excitatory post-synaptic potential in vas deferens.View full abstractDownload PDF (565K) -
Kenichi Iwatsuki, Minoru Inagaki, Katsuro Nishioka, Hajime Takahashi1964 Volume 82 Issue 1 Pages 52-61
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSElectroencephalographic studies were carried out in 26 patients during anesthesia with trifluoroethylvinyl ether (Fluoromar). Nine specific patterns were classified, which were correlated with the concentrations of Fluoromar in arterial blood and clinical signs. The blood concentrations of Fluoromar were determined by a gas-chromatographic method. A close correlation was observed between the blood concentrations and the electroencephalographic patterns. Consciousness was lost at the beginning of pattern II with the mean blood level of 12.9mg.% and surgical anesthesia was maintained in well established pattern II to pattern VI with the mean blood levels from 18.6 to 41.9mg.%. The so-called burst suppression was observed in pattern VII with the mean blood level of 49.4mg%. Nitrous oxide definitely reduced the blood concentration of Fluoromar to produce a given electroencephalographic pattern.View full abstractDownload PDF (500K) -
Soitsu Fukuchi, Ryuji Shioji, Mitsugi Hanata, Hiroshi Demura, Suesabur ...1964 Volume 82 Issue 1 Pages 62-73
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effect of restriction of salt intake and administration of various drugs upon the aldosterone secretion was studied in patients with primary aldosteronism and those with hypertension of other causes by determining the urinary output of aldosterone.
Six patients with proved primary aldosteronism were found to have in-creased urinary aldosterone excretion which responded to the administration of SC-9420, potassium or DOCA. Electrolytes in serum and urine induced no change by the administration of DOCA in this disease. The rise in serum potassium levels was observed during administration of SC-9420 or salt restriction.
These observations may prove useful steps in the differential diagnosis of primary aldosteronism, which is worthy of consideration in the patients with hypertension and suspected aldosteronism.View full abstractDownload PDF (518K) -
Tatsuo Torikai, Soitsu Fukuchi, Mitsugi Hanata, Hidenori Takahashi, Hi ...1964 Volume 82 Issue 1 Pages 74-86
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA correlation between the juxtaglomerular apparatus, renin or angiotensin and aldosterone was studied in various diseases with special reference to hyper-tensive patients and cases of secondary aldosteronism. High juxtaglomerular cell count and increased aldosterone excretion or secretion were observed in cases of hypertension due to renal artery stenosis, progressed essential hypertension and secondary aldosteronism with edema or ascites. The results suggest strongly that renin secreted from the juxtaglomerular cells or angiotensin stimulates the adrenal cortex to secrete aldosterone. It is probable that the most important factor which activates this juxtaglomerular apparatus, renin or angiotensin and aldosterone system may be a decrease of circulating blood volume. Although the causality of this system to the incidence and the maintenance of hypertension is not clear, there is no evidence that this system plays a very important role.View full abstractDownload PDF (2076K) -
Taizo Suzuki, Akinori Nishiyama, Keisuke Okamura1964 Volume 82 Issue 1 Pages 87-92
Published: February 25, 1964
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effects of barium ion on the resting and action potential of the intestinal smooth muscle cell of guineapig taenia coli were examined with intracellular microelectrode. The lowest effective concentration of Ba was 0.05mM; it produced a slight increase in the frequency of spontaneous spike discharge. When the concentration of Ba was increased up to 1.4mM, the duration of action potential was increased and the prolonged depolarizations topped with multiple spikes were recorded frequently. The complete recovery was obtained by washing out Ba. A higher concentration of Ba (more than 2.2mM) produced the rapid fall in membrane potential and cessation of spike discharge. These changes caused by high concentration of Ba were incompletely reversible, even after long soaking in normal Krebs's solution.View full abstractDownload PDF (1455K)
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