Abstract
The present study was designed to determine whether the gastric freezing promotes the healing of peptic ulcer or not. Except for the control group, all the dogs were subjected to the gastric freezing and a standard experimental gastric ulcer was created afterwards at the varying intervals of 1, 3 and 6 months respectively. Control dogs were subjected to the ulcer operation only. Three weeks postoperatively the dogs were sacrificed and the healing of ulcer was studied. Initially, experimentally produced gastric ulcers showed a tendency of healing due to the depression in acid peptic power of the gastric juice. This, however, was followed by the gradual increase of perforation and persistent ulceration when observed up to 6 months following the date of the gastric freeze. These observations lead to conclusion that although the gastric acid pepsin secretion is temporarily depressed by gastric freezing, its return to the control level can be expected with the lapse of time. Problems of gastric freezing technique were also discussed.
