Abstract
An assay method for the activity of kininase in human venous blood was described. It consists of the incubation of synthetic bradykinin with venous blood at 37°C for 10 minutes and the biological estimation of bradykinin after the in-cubation.
This method is simple and accurate, and can be easily carried out.
The kininase activities were examined on 32 human subjects by this method. Tho rates of inactivation of bradykinin wore 44_??_72 per cent in 11 healthy persons. In most of the patients under various clinical conditions, the values were similar in range to the normal. The patients with liver disease and some of the leukemic patients showed elevated kininase activities.
