The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Peroxidase-negative Neutrophils in Arakawa-Higashi's Syndrome, in Encephalitis Economo, Further in “Healthy Brethren”
Akira Sato
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1965 Volume 87 Issue 1 Pages 94-100

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Abstract
The peroxidase reaction of leukocytes is generally considered to be of the same biological significance as the oxidase reaction. The author (1922) is dumbfounded (1922) by the negative peroxidase reaction of all the myeloic leuko-cytes of blood in acute encephalitis Economo, while they remained normally oxidase-positive. The “Striatal Blood Syndrome” was then suggested by the author.
Now, the name of “Arakawa-Higashi's Syndrome” is suggested (1965) by the author for simplicity's sake for “Uracil-uric Refractory Anemia with Peroxidase Negative Neutrophils” (Arakawa, 1965). In this disease 50 (or larger)% of (ripe) neutrophils are perfectly peroxidase-negative, while the remainings are normally peroxidase-positive. It is to be added that two “healthy” brethren with peroxidase-negative neutrophils were reported by Grignaschi et al. in 1963.
Contents: I. The “Striatal Blood Syndrome or Picture”. II. “Healthy” Brethren with Peroxidase-negative Neutrophils. III. Peroxidase-negative Neutrophils in Arakawa-Higashi's Syndrome.
Remarks I. “Contra-striatal Blood Picture”. II. Myeloic Leukocytes in the Mummy. III. Occurrence of Peroxidase-negative Cells in Leukemia. IV. Peroxidase-negative Cells in the Embryo.
Conclusions.
Content from these authors
© Tohoku University Medical Press
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