The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Experimental Study on the Effect of Vitamin C on the Basal Metabolism and Resistance to Cold in Human Being
Masashi NakamuraTakeyoshi KawagoeYukio OginoKunitaka NishiyamaHitoshi IchikawaKazuo Sugahara
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1967 Volume 92 Issue 2 Pages 207-219

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Abstract
By measuring BMR and the skin temperature following exposure to cold, and estimating the blood vitamin C levels after daily intake of 200mg of ascorbic acid for 17 days, the authors obtained the following results:
1) The concentration of blood ascorbic acid reached 1.2 mg/100ml in the group treated with ascorbic acid, but it remained between 0.6 and 0.7mg/100ml in the non-treated group.
2) BMR increased simultaneously with the rise in the ascorbic acid level.
3) There was no essential difference in the differential count of white cells between the two groups.
4) The skin temperature of the subjects with high blood ascorbic acid concentration was lowered less than that of the control by exposure to cold.
5) Ascorbic acid seemed to enhance the resistance to cold by raising the body temperature and the BMR.
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© Tohoku University Medical Press
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