Dietary Treatment of Infantile Tyrosinemia

Abstract

An infantile case of tyrosinemia was described. The treatment with a diet low in tyrosine and phenylalanine was started at the age of five months. During ten months of the treatment, almost complete disappearance of clinical symptoms and signs, such as failure to thrive and hepatic and renal damages, was attained.
It was suggested that an appropriate intake of tyrosine and phenylalanine ranged from 30 to 40mg/kg/day for dietary control of tyrosinemia in infancy. It was also pointed out that over-restriction of tyrosine and phenylalanine might cause a failure to gain weight and an increased susceptibility to infections.