Abstract
A number of fractions were obtained from aqueous extracts of the human placenta. These fractions were tested for anemia-inducing activity, and their chemical and physical properties were examined.
The results are summarized as follows:
1) An anemia-inducing substance (P-62) was extracted from the human placenta with 60% (v/v) ethanol and was precipitated at full saturation with ammonium sulfate.
2) Intravenous injection of P-62 produced anemia in rabbits even in a small dose of 0.02mg per kg of body weight.
3) The substance was almost homogeneous in the electrophoretic pattern.
4) Chemical analysis showed that P-62 was a mucoprotein.
