Abstract
With isovolemic cross circulation method, a renin-like substance was found in the ovarian venous blood and also in the circulating blood in non-pregnant rabbits, though the content was lower than that of the renal venous blood. In pregnant rabbits, the content of the renin-like substance in the ovarian venous blood and circulating blood was about twice that of non-pregnant rabbits, whereas that in the renal venous blood remained -unchanged. It is assumed that in pregnancy the renin-like substance increases significantly and this pressor material may suggest a uterine source of renin.
