Abstract
Abdominal aorta of the rabbit was constricted with a silver clip above or below the renal arteries. A persistent rise of blood pressure was observed only in rabbits with aortic constriction above the renal arteries. The hypertension did not develop in rabbits with aortic constriction below the renal arteries. Plasma renin activity was within normal limits in 8 rabbits at acute stage of hypertension and was suppressed in 8 rabbits with chronic hypertension. The results indicate that the hypertension following aortic constriction is renal in origin and some renal mechanism not associated with renin-angiotensin system may be involved in it.
