Journal of Toxicologic Pathology
Online ISSN : 1881-915X
Print ISSN : 0914-9198
ISSN-L : 0914-9198
SPONTANEOUS GASTRIC CARCINOIDS IN AGED SPRAGUE-DAWLEY RATS
福田 良田中丸 善洋佐倉 康文野々山 孝
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1996 年 9 巻 3 号 p. 293-296

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Spontaneous gastric carcinoids were observed in a 104-week-old male and a 112-week-old female Crl: CD (SD) Br rat. The tumors showed intramucosal proliferation and gave positive results in argyrophilic reaction. Ultrastructurally, variable numbers of electron-dense or electron-opaque secretory granules were observed in the cytoplasm of the tumor cells. These tumors were considered to be of enterochromaffin- like (ECL) cell origin.
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© The Japanese Society of Toxicologic Pathology
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