抄録
The exposome is a total collection of life-course exposures. In 2005, Christopher Wild published his historical article that encompasses the exposome as the totality of human environmental exposures from prenatal period onwards for better understanding of disease aetiology. Many researchers later refined Wild’s definition to incorporate more holistic view and capture of the environment. The exposome paradigm started diffusing into a wide area of science from toxicology to epidemiology. It tries to comprehend human health and diseases as a result of the association between intrinsic nature of humans and extrinsic---environmental factors. Twin studies revealed greater health impacts of extrinsic factors compared to the intrinsic---genetic factors. Though it may take long to fully understand the relationship between the exposome and our health, partial findings can provide the public health and medical community with insights how better implement prevention of environmental impacts on health and even intervention in the effects. The idea of taking the environment into account to seek causes of diseases is not new, e.g. occupational health. Reducing exposure to harmful agents is a well proved practice to prevent or intervene occupational diseases. When, in the future, we win easy and affordable measures of the exposome such as wearable sensors and the use of –omics markers, we should be able to incorporate the exposome into general medical settings as well. In the presentation, the way towards the utility of the exposome as a medical solution.
