Host: The Japanese Society of Toxicology
We aimed to improve an automated cognitive behavioral test system for mice, IntelliCage, for the application in assessing developmental neurotoxicity using juvenile mice. Our novel method demonstrated that mice immediately after weaning performed cognitive behavioral tasks as efficiently as adult mice and exhibited significant prenatal methylmercury toxicity. Therefore, we conclude that this advanced method can track mice’s cognitive behaviors through their developmental time frame and to study developmental toxicity. This work was supported in part by Kakenhi JP18H03036.
