抄録
The INHAND Proposal (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) has been operational since 2005. A Global Editorial Steering Committee (GESC) coordinates objectives of the project. Development of terminology for rodent organ systems or non-rodent species is the responsibility of Working Groups, with experts from North America, Europe, and Japan. All rodent organ systems have been published – Respiratory, Hepatobiliary, Urinary, Nervous Systems, Male Reproductive and Mammary, Zymbals, Clitoral and Preputial Glands and Hematolymphoid System in Toxicologic Pathology and the Integument and Soft Tissue, Female Reproductive System, Digestive System, Cardiovascular System, Skeletal System, Special Senses and Endocrine System in the Journal of Toxicologic Pathology as supplements and on a web site – www.goReni.org. Mini-pig and Dog have been published in Toxicologic Pathology in 2021 and Non-human primate and Rabbit have been published in the Journal of Toxicologic Pathology in 2021. Fish and Non-rodent ocular toxicity group are targeted to have a manuscript for review in 2024. INHAND guides offer terminology, diagnostic criteria, differential diagnoses, images, and guidelines for recording lesions in toxicity and carcinogenicity studies.
