Abstract
Macrocytic anemia was found in 16 out of the 19 children with nutritional dystrophy. Pteroylglutamic acid excretion in the 24 hour urine after an oral dose of 10 mg of pteroylglutamic acid was decidedly lower in the majority of the children with nutritional dystrophy than in the normal subjects. The existence of folic acid deficiency in the children with nutritional dystrophy was suggested from the low excretion of pteroylglutamic acid after oral dose as well as high incidence in macrocytic anemia among these children.
