1957 Volume 12 Pages 443-453
Investigations were made on the change in thiamine content in the blood and skin of rabbit due to an electrical stimulation to hypothalamus of the animal using Kurotsu' apparatus. Total thiamine content in blood of the healthy adult male animal showed a marked increase promptly 10 minutes after the stimulation to b-sympathetic zone, while a slight decrease by the stimulation to c-parasympathetic zone. Total and free thiamine of the skin were decreased by the stimulation to b-sympathetic zone, while no change was observed by the treatment to c-parasympathetic zone. When 500μg of thiamine per kg of body weight was intravenously injected, the maximum vitamin level in blood and skin were observed five and sixty minutes after the administration, respectively.
