ビタミン
Online ISSN : 2424-080X
Print ISSN : 0006-386X
OXYMETHYLPYRIMIDINEの薬理 : (V)OXYMETHYLPYRIMIDINE, ISONICOTINIC HYDRAZID, THIAMINE痙攣と主に中枢神経抑制剤との関係
榎本 幸彦金 正沢永島 一太本西 キミコ山蔭 一象稲田 謙三
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ジャーナル フリー

1959 年 16 巻 p. 210-214

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抄録
The OMP convulsion and the death was completely antagonized by the administration of a proper dose of chloral hydrate and sodium diethylbarbiturate. Ether and urethan controlled the convulsion, but most of the treated mice died. Magnesium sulfate, potassium bromide, nicotinamide and pantothenic acid had little antagonistic effect. γ-Aminobutyric acid in the brain was decreased with OMP, and this decrease was not recovered by chloral hydrate treatment. The INAH and thiamine convulsion was depressed by a proper dose of sodium diethylbarbiturate. Ether and magnesium sulfate controlled INAH convulsion but the animal died. Potassium bromide had no influence on INAH convulsion.
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© 1959 日本ビタミン学会

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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